PIPA5100345
TALPID3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5100345-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5100345 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
TALPID3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KIAA0586
Gene Alias
JBTS23; KIAA0586; ortholog of chicken talpid{3}; protein TALPID3; SRTD14; TALPID3
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9786
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q9BVV6
Gene Symbols
KIAA0586
Immunogen
A synthesized peptide derived from human KIAA0586(Accession Q9BVV6), corresponding to amino acid residues D375-H425.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total TALPID3
- KIAA0586 also named as Talpid3 is a 1472 amino-acid protein, which belongs to Talpid3 family
- Talpid3 is a gene essential for vertebrate development
- Studies in chicken, mouse, zebrafish and human have shown that TALPID3 is a centrosomal protein, mutants null for TALPID3 fail to produce cilia, resulting in far reaching signaling defects such as polydactyly, dorsalised neural tube, craniofacial and vascular defects often due to abnormalities in Hedgehog signal transduction
- Talpid3 is absolutely required for the function of both Gli repressor and activator in the intracellular Hedgehog pathway and ciliogenesis
- TALPID3 may be identified as a subcellular maker of centrosome and needed to further studied.