WWOX Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101339-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5101339 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
WWOX
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Wwox
Gene Alias
5330426P09Rik; 9030416C10Rik; D16S432E; EIEE28; FOR; FRA16D; Fragile site FRA16D oxidoreductase; HHCMA56; PRO0128; SCAR12; SDR41C1; Short chain dehydrogenase/reductase family 41C member 1; short chain dehydrogenase/reductase family 41C, member 1; WOX1; WW domain containing oxidoreductase; WW domain-containing oxidoreductase; WW domain-containing protein WWOX; WW-domain oxidoreductase; Wwox
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
292041, 51741, 80707
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q91WL8, Q9NZC7
Gene Symbols
Wwox
Immunogen
A synthesized peptide derived from human WWOX(Accession Q9NZC7), corresponding to amino acid residues T38-P88.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total WWOX
- WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing
- This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD)
- The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate
- This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism
- The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein
- In addition, there is evidence that this gene behaves as a suppressor of tumor growth
- Alternative splicing of this gene generates transcript variants that encode different isoforms.