PIPA5101357

MRPL21 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5101357-Each-of-1 In Stock ₹ 46,502.50

PIPA5101357 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

MRPL21

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MRPL21

Gene Alias

39S ribosomal protein L21, mitochondrial; BC028768; D9Wsu149; L21mt; Mitochondrial large ribosomal subunit protein bL21m; mitochondrial ribosomal protein L21; Mrpl21; MRP-L21; Unknown (protein for MGC:133585)

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

219927, 309140, 353242

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q7Z2W9, Q9D1N9

Gene Symbols

MRPL21

Immunogen

A synthesized peptide derived from human MRPL21(Accession Q7Z2W9), corresponding to amino acid residues R23-T73.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total MRPL21
  • Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion
  • Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit
  • They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed
  • Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA
  • Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology
  • This gene encodes a 39S subunit protein
  • Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD).