ABCD4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101446-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5101446 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
ABCD4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ABCD4
Gene Alias
69 kDa peroxisomal ABC-transporter; ABC41; ABCD4; ATP binding cassette subfamily D member 4; ATP-binding cassette sub-family D member 4; ATP-binding cassette, subfamily D (ALD), member 4; ATP-binding cassette, sub-family D (ALD), member 4; ATP-binding cassette, sub-family D, member 4; EST352188; MAHCJ; P69r; P70R; P79R; Peroxisomal membrane protein 1-like; Peroxisomal membrane protein 69; peroxisomal membrane protein, 70 kDa-related; PMP69; PMP70-related protein; Pxmp1l; PXMP1-L
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19300, 5826
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O14678, O89016
Gene Symbols
ABCD4
Immunogen
A synthesized peptide derived from human ABCD4(Accession O14678), corresponding to amino acid residues R112-S162.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total ABCD4
- The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1-4 that are known to be present in the human peroxisome membrane
- All four proteins are ABC half-transporters, which dimerize to form an active transporter
- A mutation in the ABCD1 gene causes X-linked adreno-leukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage
- ABCD2 in mouse is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD
- The peroxisomal membrane comprises two quantitatively major proteins, PMP22 and ABCD3
- ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors
- ABCD1 localizes to peroxisomes
- ABCB7 is a half-transporter involved in the transport of heme from the mitochondria to the cytosol.