PIPA5101597

GABRA4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5101597-Each-of-1 In Stock ₹ 46,502.50

PIPA5101597 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

GABRA4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GABRA4

Gene Alias

GABA(A) receptor; GABA(A) receptor subunit alpha-4; GABA(A) receptor, alpha 4; GABA-A receptor alpha-4 subunit; GABAARalpha4; Gabra4; Gabra-4; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, alpha 4; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 4; gamma-aminobutyric acid A receptor alpha 4; gamma-aminobutyric acid receptor subunit alpha-4; gamma-aminobutyric acid type A receptor alpha4 subunit

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

140675, 14397, 2557

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P28471, P48169, Q9D6F4

Gene Symbols

GABRA4

Immunogen

A synthesized peptide derived from human GABRA4(Accession P48169), corresponding to amino acid residues A14-R64.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total GABRA4
  • Gamma-aminobutyric acid is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels
  • Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor
  • At least 16 distinct subunits of GABA-A receptors have been identified
  • This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1
  • Alternatively spliced transcript variants encoding different isoforms have been found in this gene.