ZFYVE19 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101963-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5101963 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
ZFYVE19
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ZFYVE19
Gene Alias
1500041L05Rik; abscission/NoCut checkpoint regulator; ANCHR; MLL partner containing FYVE domain; MPFYVE; Zfyve19; Zinc finger FYVE domain-containing protein 19; zinc finger FYVE-type containing 19; zinc finger, FYVE domain containing 19
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
72008, 84936
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q96K21, Q9DAZ9
Gene Symbols
ZFYVE19
Immunogen
A synthesized peptide derived from human ZFYVE19(Accession Q96K21), corresponding to amino acid residues E315-Q365.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total ZFYVE19
- Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage
- Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis
- Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.