PIPA5102429

IFN beta Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102429-Each-of-1 In Stock ₹ 50,863.50

PIPA5102429 - Each of 1

₹ 50,863.50

In Stock

Quantity

1

Base Price: ₹ 50,863.50

GST (18%): ₹ 9,155.43

Total Price: ₹ 60,018.93

Antigen

IFN beta

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ifnb1

Gene Alias

Fibroblast interferon; Ifb; IFF; IFN b; IFN β; IFNB; Ifnb1; IFNbeta; IFN-beta; IFNβ; Interferon b; Interferon beta; interferon beta 1; interferon beta 1, fibroblast; interferon beta protein; interferon, beta 1; interferon, beta 1, fibroblast; interferon-beta; RP11-113D19.1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15977, 24481, 3456

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P01574, P01575, P70499

Gene Symbols

Ifnb1

Immunogen

A synthesized peptide derived from human IFNB1(Accession P01574), corresponding to amino acid residues F71-T121.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total IFNB1
  • Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response
  • IFNs can also inhibit the development of tumors
  • IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes
  • More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta
  • IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.