GAS2L1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5102586-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5102586 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
GAS2L1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GAS2L1
Gene Alias
4930500E24Rik; D0Jmb1; Gar22; GAS2L1; GAS2-like protein 1; GAS2-related protein; GAS2-related protein on chromosome 22; growth arrest specific 2 like 1; growth arrest-specific 2 like 1; growth arrest-specific protein 2-like 1; TU-71.1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10634, 360973, 78926
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q8JZP9, Q99501
Gene Symbols
GAS2L1
Immunogen
A synthesized peptide derived from human GAS2L1(Accession Q99501), corresponding to amino acid residues C624-R674.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total GAS2L1
- The Gas2 protein is thought to play a role in apoptosis by acting as a cell death substrate for caspases
- Gas2, a component of the microfilament system, is cleaved by a caspase (caspase-3 or caspase-7) at Asparagine 278 during apoptosis
- The cleaved form of Gas2 dramatically induces the re-arrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells
- Gas2 is a cytoskeleton and peripheral membrane protein that co-localizes with Actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts
- Gas2 is mainly membrane-associated, but when hyperphosphorylated it will accumulate at membrane ruffles, indicating Gas2 involvement in that process
- Gar22 (Gas2-related protein on chromosome 22), also designated growth arrest-specific protein 2-like 1 (Gas2-like1), belongs to the Gas2 family and contains one CH (calponinhomo-logy) domain
- It is thought to be involved in the cross-linking of microtubules and microfilaments.