Caspase 5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5102876-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5102876 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Caspase 5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CASP5
Gene Alias
CASP5; CASP-5; caspase 5; caspase 5, apoptosis-related cysteine peptidase; caspase 5, apoptosis-related cysteine protease; caspase-5; Caspase-5 subunit p10; Caspase-5 subunit p20; ICE(rel)III; ICE(rel)-III; ICEREL-III; ICH3; ICH-3; Protease ICH-3; protease TY; TY protease
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
838
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P51878
Gene Symbols
CASP5
Immunogen
A synthesized peptide derived from human CASP5(Accession P51878), corresponding to amino acid residues S118-R168.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total Caspase 5
- Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies
- Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens
- Members of this subfamily include caspase-1, -4, -5, and -12
- Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1-b and IL-18
- Caspase-5 can interact with caspase-1; both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1-b
- Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-gamma.