PABPN1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5102924-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5102924 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PABPN1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PABPN1
Gene Alias
mPABII; Nuclear poly(A)-binding protein 1; OPMD; PAB2; PABII; PABP2; PABP-2; Pabp3; PABPN1; poly(A) binding protein 2; poly(A) binding protein II; poly(A) binding protein nuclear 1; poly(A) binding protein, nuclear 1; poly(A)-binding protein 2; poly(A)-binding protein II; polyA binding protein II; polyadenylate-binding nuclear protein 1; Polyadenylate-binding protein 2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
54196, 8106
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q86U42, Q8CCS6
Gene Symbols
PABPN1
Immunogen
A synthesized peptide derived from human PABPN1(Accession Q86U42), corresponding to amino acid residues P252-W302.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total PABP2
- This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails
- The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt
- At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm
- This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease
- Related pseudogenes have been identified on chromosomes 19 and X
- Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.