ROR2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5102946-Each-of-1 | In Stock | ₹ 47,036.50 |
PIPA5102946 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,036.50
GST (18%): ₹ 8,466.57
Total Price: ₹ 55,503.07
Antigen
ROR2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ROR2
Gene Alias
BDB; BDB1; mRor2; neurotrophic tyrosine kinase receptor-related 2; neurotrophic tyrosine kinase, receptor related 2; neurotrophic tyrosine kinase, receptor-related 2; NTRKR2; receptor tyrosine kinase like orphan receptor 2; receptor tyrosine kinase-like orphan receptor 2; ROR2; Tyrosine-protein kinase transmembrane receptor ROR2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26564, 4920
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q01974, Q9Z138
Gene Symbols
ROR2
Immunogen
A synthesized peptide derived from human ROR2(Accession Q01974), corresponding to amino acid residues L424-R474.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total ROR2
- ROR2 (receptor tyrosine kinase-like orphan receptor 2) is a type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors
- It is thought to be involved in the early formation of the chondrocytes and cartilage and growth plate development
- This Type I membrane protein is expressed at high levels during early embryonic development
- The expression levels drop strongly around day 16 and there are only very low levels in adult tissues
- Defects in ROR2 are a cause of brachydactyly type B1 (BDB1)
- BDB1 is an autosomal dominant skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails
- In BDB1 the middle phalanges are short but in addition the terminal phalanges are rudimentary or absent
- Both fingers and toes are affected
- The thumbs and big toes are usually deformed
- Defects in ROR2 are a cause of recessive Robinow syndrome (RRS)
- RRS is an autosomal disorder characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly and a dysmorphic facial appearance
- The protein contains 1 frizzled (FZ) domain, 1 immunoglobulin-like C2-type domain, and 1 kringle domain.