WRN Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103075-Each-of-1 | In Stock | ₹ 45,345.50 |
PIPA5103075 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,345.50
GST (18%): ₹ 8,162.19
Total Price: ₹ 53,507.69
Antigen
WRN
Classification
Polyclonal
Conjugate
Unconjugated
Gene
WRN
Gene Alias
AI846146; DKFZp686C2056; DNA helicase, RecQ-like type 3; exonuclease WRN; RecQ protein-like 2; RecQ3; RECQL2; RECQL3; RGD1564788; similar to Werner syndrome helicase homolog; Werner syndrome ATP-dependent helicase; Werner syndrome ATP-dependent helicase homolog; Werner syndrome homolog (human); Werner syndrome RecQ like helicase; Werner syndrome, RecQ helicase-like; WRN
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22427, 7486
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O09053, Q14191
Gene Symbols
WRN
Immunogen
A synthesized peptide derived from human WRN(Accession Q14191), corresponding to amino acid residues L927-F977.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total WRN
- This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases
- DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair
- This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization
- It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease
- Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks
- Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.