PIPA5103140

HOXB4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103140-Each-of-1 In Stock ₹ 46,502.50

PIPA5103140 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

HOXB4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HOXB4

Gene Alias

homeo box 2F; homeo box B4; homeo box B4a; homeobox B4; homeobox B4a; homeobox gene B-4; homeobox protein Hox-2.6; Homeobox protein Hox-2F; homeobox protein Hox-B4; Homeobox protein Hox-B4a; homeobox protein Zf-13; HOX2; Hox-2.6; HOX2F; Hoxb4; HOX-B4; Hoxb-4; Hoxb4 protein; hoxb4a; Hoxb4a variant 2; RGD1560113; sb:eu512; Z-17; zf13; ZF-13

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15412, 3214

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P10284, P17483

Gene Symbols

HOXB4

Immunogen

A synthesized peptide derived from human HOXB4(Accession P17483), corresponding to amino acid residues S4-F54.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total HoxB4
  • HOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation
  • HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs
  • Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype
  • Activation of WNT signaling in HSCs induced increased expression of HOXB4
  • Perturbations of HOX gene expression can cause leukemia.