PIPA5103216
NARF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103216-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5103216 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
NARF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NARF
Gene Alias
4430402O11Rik; IOP2; iron-only hydrogenase-like protein 2; Narf; Nuclear prelamin A recognition factor; prenyl-dependent prelamin A binding protein; RGD1310894
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26502, 360681
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q2YDU6, Q9UHQ1
Gene Symbols
NARF
Immunogen
A synthesized peptide derived from human NARF(Accession Q9UHQ1), corresponding to amino acid residues I356-D406.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total NARF
- Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends
- Prenylation was initially believed to be important only for membrane attachment
- However, another role for prenylation appears to be its importance in protein-protein interactions
- The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins
- Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif
- This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A
- The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain
- It may be a component of a prelamin A endoprotease complex
- The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina
- It shares limited sequence similarity with iron-only bacterial hydrogenases
- Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing.