PIPA5103286

CDKL5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103286-Each-of-1 In Stock ₹ 46,680.50

PIPA5103286 - Each of 1

₹ 46,680.50

In Stock

Quantity

1

Base Price: ₹ 46,680.50

GST (18%): ₹ 8,402.49

Total Price: ₹ 55,082.99

Antigen

CDKL5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CDKL5

Gene Alias

BC038161; Cdkl5; CFAP247; cyclin dependent kinase 5 transcript; cyclin dependent kinase like 5; cyclin-dependent kinase-like 5; EIEE2; ISSX; RP1-245G19.3; serine/threonine kinase 9; serine/threonine-protein kinase 9; STK9

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

382253, 6792

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O76039, Q3UTQ8

Gene Symbols

CDKL5

Immunogen

A synthesized peptide derived from human CDKL5(Accession O76039), corresponding to amino acid residues E666-Y716.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total CDKL5
  • CDKL5 serine/threonine kinase (STK9) is associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome and Rett syndrome (RTT)
  • CDKL5 can control nuclear speckle morphology by regulating the phosphorylation state of splicing regulatory proteins, and may be involved indirectly in pre-mRNA processing by controlling splicing factor dynamics
  • The mutations in CDKL5 are major cause of infantile spasms and early epileptic seizures in female patients, and of a later intractable seizure disorder.