PIPA5103377

HTR2A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103377-Each-of-1 In Stock ₹ 48,193.50

PIPA5103377 - Each of 1

₹ 48,193.50

In Stock

Quantity

1

Base Price: ₹ 48,193.50

GST (18%): ₹ 8,674.83

Total Price: ₹ 56,868.33

Antigen

HTR2A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Htr2a

Gene Alias

5-HT-2; 5Ht-2; 5-HT2 receptor; 5-HT2A; 5-HT-2A; 5HT2A Receptor; 5-HT2A receptor; 5-HT2A/2C; 5-HT2A/2C receptor; 5-hydroxytryptamine (serotonin) receptor 2A; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled; 5-hydroxytryptamine 2 receptor; 5-hydroxytryptamine receptor 2A; E030013E04; Htr2; Htr-2; HTR2A; serotonin 5HT-2 receptor; serotonin 5-HT-2A receptor; serotonin receptor 2A; SR2A

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29595, 3356

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P14842, P28223

Gene Symbols

Htr2a

Immunogen

A synthesized peptide derived from human HTR2A(Accession P28223), corresponding to amino acid residues I252-E302.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total 5HT2A Receptor
  • In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively
  • Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors
  • The SR-2 receptors are comprised of three subtypes, SR-2A, SR-2B and SR-2C, which activate phospholipase C and release intracellular stores of calcium in response to serotonin
  • SR-2A has a specific role in tracheal smooth muscle contraction, bronchoconstriction and mediating aldosterone production, and it is also thought to play a role in several psychiatric disorders, including depression and schizophrenia
  • SR-2B is expressed in embryonic and adult cardiovascular tissues, gut and brain and plays an important role in the pathology of cardiac disorders
  • SR-2C is thought to mediate the effects of atypical antipsychotic drugs.