COX5B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103384-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5103384 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
COX5B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
COX5B
Gene Alias
COX5B; COXVB; cytochrome c oxidase polypeptide Vb; cytochrome c oxidase polypeptide VB, mitochondrial; cytochrome c oxidase polypeptide VIa; cytochrome c oxidase precursor (EC 1.9.3.1); cytochrome c oxidase subunit 5B; cytochrome c oxidase subunit 5B, mitochondrial; cytochrome c oxidase subunit Vb; cytochrome c oxidase subunit VIA*
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12859, 1329, 94194
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P10606, P12075, P19536
Gene Symbols
COX5B
Immunogen
A synthesized peptide derived from human COX5B(Accession P10606), corresponding to amino acid residues A14-V64.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total COX5B
- The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, μgtimately resulting in the production of water
- The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear
- Found in the inner mitochondrial membrane, COX5 is the heme A-containing chain of the oxidase family that converts one molecule of oxygen and four molecules of hydrogen to two molecules of water
- Two isoforms of COX5 exist, COX5a and COX5b
- When oxygen levels within the cell are high, transcription of COX5a (the aerobic isoform) is up-regulated as the rate of cellular respiration increases
- Conversely, when oxygen levels are low, COX5b (the hypoxic isoform) transcription increases and functions to maximize the turnover rate of the COX apoenzyme.