PIPA5103477

TIAF1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103477-Each-of-1 In Stock ₹ 46,502.50

PIPA5103477 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

TIAF1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TIAF1

Gene Alias

12 kDa TGF-beta-1-induced antiapoptotic factor; MAJN; molecule associated with Jak-3 N-terminal; MYO18A; MYSPDZ; SPR210; TGFB1-induced anti-apoptotic factor 1; TGF-beta-1-induced antiapoptotic factor 1; TIAF; TIAF1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9220

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O95411

Gene Symbols

TIAF1

Immunogen

A synthesized peptide derived from human TIAF1(Accession O95411), corresponding to amino acid residues N80-G115.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total TIAF1
  • TIAF-1 (TGFB1-induced anti-apoptotic factor 1), also known as MYO18A, is a TGFB1-induced anti-apoptotic factor that functions to inhibit the cytotoxic effects of TNF-alpha, TRADD and FADD
  • It localizes to the nucleus and significantly up-regulated in activated helper T lymphocytes (TH2) in chronic kidney and liver allograft rejection
  • Suppression of TIAF1 expression by siRNA prevents UV irradiation-mediated p53 phosphorylation and nuclear translocation
  • TIAF1 is essential in the p53- and WOX1-mediated cell death and shows an aggregation-dependent control of tumor progression and metastasis, and regulation of cell death.