PIPA5103575

ADAMTS10 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103575-Each-of-1 In Stock ₹ 45,434.50

PIPA5103575 - Each of 1

₹ 45,434.50

In Stock

Quantity

1

Base Price: ₹ 45,434.50

GST (18%): ₹ 8,178.21

Total Price: ₹ 53,612.71

Antigen

ADAMTS10

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ADAMTS10

Gene Alias

9430006O18; a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 10; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10; a disintegrin-like and metalloprotease with thrombospondin type 1 motif, 10; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 10; ADAM metallopeptidase with thrombospondin type 1 motif, 10; ADAMs; ADAM-TS 10; ADAMTS10; Adam-ts10; ADAMTS-10; AW045948; metalloendopeptidases; WMS; WMS1; zinc metalloendopeptidase; Znmp

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

224697, 81794

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P58459, Q9H324

Gene Symbols

ADAMTS10

Immunogen

A synthesized peptide derived from human ADAMTS10(Accession Q9H324), corresponding to amino acid residues G903-W953.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total ADAMTS10
  • ADAMTS (a disintegrin and metalloproteinase domain with Thrombospondin type-1 modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer (1-3)
  • Embryogenesis, morphological growth changes, inflammation, tumor invasion and metastasis involve the breakdown and remodeling of the extracellular matrix
  • This degradation is due to the family of enzymes known as the matrix metalloproteinases (MMPs), which are related to ADAMTS subtypes
  • ADAMTS protein family members contain an amino-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a carboxy-terminus that contains a varying number of thrombospondin type-1 (TSP-1) motifs (1-3)
  • ADAMTS genes are primarily expressed in fetal tissues, including the lung, kidney and liver (1-3)
  • The human ADAMTS10 gene maps to chromosome 19p13.3 (4)
  • The human ADAMTS19 gene maps to chromosome 5q31 (1,5).