PIPA5103696

ARPP19 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103696-Each-of-1 In Stock ₹ 46,502.50

PIPA5103696 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

ARPP19

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ARPP19

Gene Alias

19kDa; 2700024H10Rik; Arpp12; ARPP16; ARPP-16; Arpp19; ARPP-19; AW559096; cAMP regulated phosphoprotein 19; cAMP regulated phosphoprotein 19kDa; cAMP-regulated phosphoprotein 19; cAMP-regulated phosphoprotein 19kDa; cAMP-regulated phosphoprotein ARPP-19; cAMP-regulated phosphoprotein, 19kDa; cyclic AMP phosphoprotein, 19 kD; cyclic AMP phosphoprotein, 19 kDa; cyclic AMP phosphoprotein, 19kD; ENSAL

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10776, 59046, 60336

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P56211, P56212, Q712U5

Gene Symbols

ARPP19

Immunogen

A synthesized peptide derived from human ARPP19(Accession P56211), corresponding to amino acid residues M1-K42.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total ARPP19
  • Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis
  • When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase
  • May indirectly enhance GAP-43 expression by binding to the NGF-regulatory region of its mRNA.