CCP110 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103725-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5103725 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CCP110
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CCP110
Gene Alias
6330503K22Rik; AA415922; AI427129; AW557948; CCP110; centriolar coiled coil protein 110; centriolar coiled coil protein 110kDa; centriolar coiled-coil protein 110; centriolar coiled-coil protein 110kDa; centriolar coiled-coil protein of 110 kDa; Centriolin; centrosomal protein CP110; centrosomal protein of 110 kDa; CEP1; Cep110; CNTRL; CP110; FAN; Kiaa0419; RGD1310509
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
101565, 361634, 9738
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O43303, Q7TSH4
Gene Symbols
CCP110
Immunogen
A synthesized peptide derived from human CCP110(Accession O43303), corresponding to amino acid residues A866-Q916.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total CEP110
- Necessary for centrosome duplication at different stages of procentriole formation
- Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064)
- Also involved in promoting ciliogenesis
- May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation
- Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425)
- [UniProt]