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PIPA5104234

GTF2H2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5104234-Each-of-1 In Stock ₹ 46,502.50

PIPA5104234 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

GTF2H2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Gtf2h2

Gene Alias

44kDa; basal transcription factor 2, p44 subunit; basic transcription factor 2 44 kDa subunit; BTF2; BTF2 p44; BTF2P44; BTF2-p44; general transcription factor II H, polypeptide 2; general transcription factor II H, polypeptide 2 (44 kDa subunit); general transcription factor IIH polypeptide 2; General transcription factor IIH subunit 2; general transcription factor IIH, polypeptide 2; general transcription factor IIH, polypeptide 2 (44 kDa subunit); general transcription factor IIH, polypeptide 2, 44kD subunit; general transcription factor IIH, polypeptide 2, 44kDa; Gtf2h2; p44; T-BTF2P44; TFIIH; TFIIH basal transcription factor complex p44 subunit

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23894, 294693, 2966

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

A0JN27, Q13888, Q9JIB4

Gene Symbols

Gtf2h2

Immunogen

A synthesized peptide derived from human GTF2H2(Accession Q13888), corresponding to amino acid residues M1-E48.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total TF2H2
  • Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors
  • Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII
  • TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities
  • The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34
  • Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1
  • Both p89 and p80 have ATP-dependent helicase activity
  • The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.