Phospho-SF1 (Ser80, Ser82) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104263-Each-of-1 | In Stock | ₹ 41,518.50 |
PIPA5104263 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,518.50
GST (18%): ₹ 7,473.33
Total Price: ₹ 48,991.83
Antigen
Phospho-SF1 (Ser80, Ser82)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SF1
Gene Alias
BBP; D11S636; M ZFM1; Mammalian branch point-binding protein; MBBP; MZFM; SF; SF1; Splicing factor 1; transcription factor ZFM1; WBP4; wu:fc09f06; ZCCHC25; ZFM1; Zfp162; Zinc finger gene in MEN1 locus; zinc finger protein 162; ZNF162
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
117855, 22668, 7536
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q15637, Q64213
Gene Symbols
SF1
Immunogen
A synthesized peptide derived from human SF1(Accession Q15637), corresponding to amino acid residues around phosphorylated Ser82.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of SF1 only when phosphorylated at Ser80/82
- Splicing factor 1 is a nuclear pre-mRNA splicing factor
- The protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly
- It also plays a role in nuclear pre-mRNA retention and transcriptional repression
- The protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain
- Alternative splicing results in multiple transcript variants.