SLC22A4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104433-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5104433 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
SLC22A4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SLC22A4
Gene Alias
ergothioneine transporter; ET transporter; ETT; integral membrane transport protein; LSTP-Like 2; Octn1; organic cation transporter 1; organic cation transporter OCTN1; organic cation/carnitine transporter 1; SLC22A4; solute carrier family (organic cation transporter), member 4; solute carrier family 22 (organic cation transporter), member 4; solute carrier family 22 (organic cation/ergothioneine transporter), member 4; solute carrier family 22 (organic cation/zwitterion transporter), member 4; solute carrier family 22 member 4; UT2H
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
30805, 6583
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q9H015, Q9Z306
Gene Symbols
SLC22A4
Immunogen
A synthesized peptide derived from human SLC22A4(Accession Q9H015), corresponding to amino acid residues S510-F551.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total SLC22A4
- Carnitine (b-hydroxy-g-trimethylaminobutyrate) is a small, highly polar compound that aids in the b-oxidation of long-chain fatty acids
- Organic cation/carnitine transporters (OCTN) assist in the elimination of cationic compounds, including xenobiotics, and transport carnitine for reabsorption in the kidney
- Similar to organic cation transporters (OCT), OCTN proteins localize to the plasma membrane of epithelial cells
- OCTN1 is expressed in kidney, trachea, bone marrow and fetal liver
- OCTN2 is abundantly expressed in kidney, skeletal muscle, placenta and heart
- OCTN3 is strongly expressed in testis and weakly expressed in kidney
- The gene encoding human OCTN1 maps to chromosome 5 and the gene encoding human OCTN2 maps to chromosome 5q31
- Mutations in the gene encoding OCTN2 leads to systemic carnitine deficiency (SCD), an autosomal recessive disorder characterized by cardiomyopathy, skeletal myopathy, lethargy, hypoglycemia and hyperammonemia.