PIPA5104737

Phospho-TK1 (Ser13) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5104737-Each-of-1 In Stock ₹ 46,502.50

PIPA5104737 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-TK1 (Ser13)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TK1

Gene Alias

D530002A18Rik; EC 2.7.1.21; KITH; thymidine kinase 1; thymidine kinase 1 soluble isoform; thymidine kinase 1, soluble; thymidine kinase, cytosolic; thymidine kinase-1; Tk; Tk1; Tk-1; Tk1a; Tk1b; TK2

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21877, 24834, 7083

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P04183, P04184, P27158

Gene Symbols

TK1

Immunogen

A synthesized peptide derived from human TK1(Accession P04183), corresponding to amino acid residues around phosphorylated Ser13.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of Thymidine Kinase 1/TK1 only when phosphorylated at Serine 13
  • Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells
  • Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA
  • Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is also used to select hybridoma cell lines in the production of monoclonal antibodies
  • Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division.