Phospho-ATF2 (Thr73, Thr55) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104806-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5104806 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-ATF2 (Thr73, Thr55)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Atf2
Gene Alias
Activating 2; Activating transcription factor 2; activating transcription factor 2 splice variant ATF2-var2; ATF2; Atf-2; cAMP response element-binding protein CRE-BP1; cAMP responsive element binding protein 2, formerly; cAMP-dependent transcription factor ATF-2; CREB2; CREB-2; CRE-BP; CREBP1; CRE-BP1; Cyclic AMP-dependent transcription factor ATF-2; cyclic AMP-responsive element-binding protein 2; D130078H02Rik; D18875; HB16; Histone acetyltransferase ATF2; MGC111558; mXBP; MXBP protein; OTTHUMP00000205345; OTTHUMP00000205347; OTTHUMP00000205348; OTTHUMP00000205350; OTTHUMP00000205352; OTTHUMP00000205353; OTTHUMP00000205354; Tg(Gzma-Klra1)7Wum; TREB7
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11909, 1386, 81647
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P15336, P16951, Q00969
Gene Symbols
Atf2
Immunogen
A synthesized peptide derived from human ATF2(Accession P15336), corresponding to amino acid residues around phosphorylated Thr73.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of ATF2 only when phosphorylated at Threonine 73 or 55
- The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins
- ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways
- Various forms of cellular stress, including genotoxic agents, inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2
- Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71
- Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2.