Phospho-PKC Pan (Thr497) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104818-Each-of-1 | In Stock | ₹ 44,099.50 |
PIPA5104818 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,099.50
GST (18%): ₹ 7,937.91
Total Price: ₹ 52,037.41
Antigen
Phospho-PKC Pan (Thr497)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Prkch
Gene Alias
14 - 3 - 3 - zeta isoform; 14-3-3-zetaisoform; 2310021H13Rik; 5830406C15Rik; A130035A12Rik; A130082F03Rik; AAG6; aging-associated gene 6; AI098070; AI385711; AI427505; AI875142; ALPS3; aPKClambda; aPKC-lambda/iota; aPKCzeta; atypical protein kinase C; atypical protein kinase C-lambda/iota; AW494342; C80388; CVID9; D14Ertd420e; DXS1179E; MAY1; mKIAA4165; nPKC-delta; nPKC-epsilon; nPKC-eta; nPKC-iota; nPKC-theta; nPKC-zeta; PKC; PKC theta; PKC zeta; PKC[d]; PKC[e]; PKC-0; PKC2; Pkca; PKC-A; PKC-alpha; Pkcb; PKC-B; PKC-beta; Pkcc; PKCD; PKCdelta; Pkce; Pkcea; PKCepsilon; PKCG; PKCgamma; PKC-gamma; Pkch; PKCI; PKCL; PKC-L; PKClambda; Pkcq; PKCtheta; PKC-theta; Pkcz; PKC-ZETA; PRKACA; Prkc; PRKCA; Prkcb; Prkcb1; Prkcb2; Prkcc; Prkcd; Prkce; PRKCG; Prkch; PRKCI; PRKCL; PRKC-lambda/iota; Prkcq; PRKCT; Prkcz; protein kinase C alpha; protein kinase C alpha type; protein kinase C beta; protein kinase C beta I; protein kinase C beta II; protein kinase C beta type; protein kinase C beta-II; protein kinase C delta; protein kinase C delta type; Protein kinase C delta type catalytic subunit; Protein kinase C delta type regulatory subunit; protein kinase C delta variant IX; protein kinase C delta VIII; protein kinase C epsilon; protein kinase C epsilon type; protein kinase C eta; protein kinase C eta type; protein kinase C gamma; protein kinase C gamma type; protein kinase C iota; protein kinase C iota type; protein kinase C theta; protein kinase C theta type; protein kinase C type I (gamma type); protein kinase C zeta; protein kinase C zeta subspecies; protein kinase C zeta type; protein kinase C, alpha; protein kinase C, beta; protein kinase C, beta 1; protein kinase C, beta 1 polypeptide; protein kinase C, delta; protein kinase C, delta IV; protein kinase C, delta V; protein kinase C, epsilon; protein kinase C, eta; protein kinase C, gamma; protein kinase C, iota; protein kinase C, lambda; protein kinase C, theta; protein kinase C, zeta; protein kinase C[d]; protein kinase c-alpha; protein kinase C-eta; r14-3-3; R74924; R75156; RATPKCI; SCA14; SDK1; Sphingosine-dependent protein kinase-1; Tyrosine-protein kinase PRKCD; zetaPKC
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
170538, 18750, 18751, 18752, 18753, 18754, 18755, 18759, 18761, 18762, 24680, 24681, 25023, 25522, 29340, 5578, 5579, 5580, 5581, 5582, 5583, 5584, 5588, 5590, 81749, 84006, 85420
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
F1M7Y5, P05129, P05696, P05771, P09215, P09216, P09217, P16054, P17252, P20444, P23298, P24723, P28867, P41743, P63318, P63319, P68403, P68404, Q02111, Q02156, Q02956, Q04759, Q05513, Q05655, Q62074, Q64617, Q9WTQ0
Gene Symbols
Prkca, PRKCB, PRKCD, PRKCE, PRKCG, Prkch, Prkci, PRKCQ, PRKCZ
Immunogen
A synthesized peptide derived from human PRKCA(Accession P17252), corresponding to amino acid residues around phosphorylated Thr497.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of PKC-pan only when phosphorylated at Threonine 497
- Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function
- PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids
- Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC
- PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms ( alpha, betaI, betaII and gamma) and novel (n) PKC isoforms ( delta, epsilon, zeta, eta and theta)
- Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies
- For instance, the kinase activities of nPKC delta and epsilon are independent of Ca2+.