PIPA5104881

Phospho-VEGF Receptor 2 (Tyr1059) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5104881-Each-of-1 In Stock ₹ 41,607.50

PIPA5104881 - Each of 1

₹ 41,607.50

In Stock

Quantity

1

Base Price: ₹ 41,607.50

GST (18%): ₹ 7,489.35

Total Price: ₹ 49,096.85

Antigen

Phospho-VEGF Receptor 2 (Tyr1059)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KDR

Gene Alias

6130401C07; CD309; CD309 antigen; fetal liver kinase 1; fetal liver kinase-1; FLK1; Flk-1; FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2); FLK1 kinase insert domain receptor (VEGF receptor 2); flk-1 type VEGF receptor; KDR; kinase insert domain protein receptor; kinase insert domain receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); kinase NYK; Krd-1; Ly73; protein-tyrosine kinase receptor flk-1; sCD309; soluble CD309; soluble vascular endothelial growth factor receptor 2; soluble VEGFR 2; soluble VEGFR2; sVEGFR-2; tyrosine kinase growth factor receptor; vascular endotheial growth factor 2; vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor- 2; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; VEGF R2; VEGF receptor-2; VEGFR; VEGFR2; VEGFR-2

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16542, 25589, 3791

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O08775, P35918, P35968

Gene Symbols

KDR

Immunogen

A synthesized peptide derived from human KDR(Accession P35968), corresponding to amino acid residues around phosphorylated Tyr1059.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of VEGFR2 only when phosphorylated at Tyrosine 1059
  • KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase
  • It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors
  • FLK1 (VEGF Receptor 2) encodes one of the two receptors of the VEGF
  • This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase
  • The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc
  • Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.