PIPA5104910

Phospho-Crk (Tyr221) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5104910-Each-of-1 In Stock ₹ 46,502.50

PIPA5104910 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-Crk (Tyr221)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mapk14

Gene Alias

Adapter molecule crk; avian sarcoma virus CT10 (v-crk) oncogene homolog; c-Crk; CRK; CRK proto-oncogene, adaptor protein; CRK1; Crk3; Crk-I; CRKII; Crk-II; CrkIII; Crk-III; Crko; CSAID-binding protein; Csaids binding protein; CSBP; Csbp1; CSBP2; CSPB1; CT-10 related kinase 3; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; cytokine suppressive anti-inflammatory drug-binding protein; cytokine-supressive anti-inflammatory drug binding protein; Exip; Hog; I79_016605; MAP kinase 14; MAP kinase 2; MAP kinase Mxi2; MAP kinase p38 alpha; MAPK 14; MAPK14; MAX-interacting protein 2; mitogen activated protein kinase 14; mitogen-activated protein kinase 14; mitogen-activated protein kinase 14A; mitogen-activated protein kinase p38 alpha; MXI2; p38; p38 alpha; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38a; p38ALPHA; p38-alpha; p38alpha Exip; p38Hog; p38MAPK; PRKM14; PRKM15; Prot

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12928, 1398, 1432, 26416, 54245, 81649

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P46108, P47811, P70618, Q16539, Q63768, Q64010

Gene Symbols

Crk, Mapk14

Immunogen

A synthesized peptide derived from human CRK(Accession P46108), corresponding to amino acid residues around phosphorylated Tyr221.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of Crk p38 only when phosphorylated at Tyrosine 221
  • The Crk-I and Crk-II forms differ in their biological activities
  • Crk-II has less transforming activity than Crk-I
  • Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner
  • Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4
  • May regulate the EFNA5-EPHA3 signaling.