Phospho-NFATC3 (Ser165) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104980-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5104980 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-NFATC3 (Ser165)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NFATC3
Gene Alias
C80703; D8Ertd281e; NFAC3; NFAT4; NF-AT4; NFATC3; NF-ATc3; NFATx; NFC3; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3; nuclear factor of activated T-cells 3; nuclear factor of activated T-cells c3 isoform IE-Xa; nuclear factor of activated T-cells, cytoplasmic 3; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3; T cell transcription factor NFAT4; T-cell transcription factor NFAT4
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18021, 361400, 4775
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P97305, Q12968
Gene Symbols
NFATC3
Immunogen
A synthesized peptide derived from human NFATC3(Accession Q12968), corresponding to amino acid residues around phosphorylated Ser165.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of NFAT4 only when phosphorylated at Serine 165
- This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance
- mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD)
- When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons
- This protein is located only in the cytoplasm
- When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping
- Use of multiple polyadenylation sites has been noted for this gene.