CRBN Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5106287-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5106287 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CRBN
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CRBN
Gene Alias
2610203G15Rik; 2900045O07Rik; AD-006; AF229032; AW108261; cereblon; CRBN; DKFZp781K0715; MGC27358; MRT2; MRT2A; novel lethal; piL; protein cereblon; Protein PiL; protein x 0001
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
297498, 51185, 58799
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q56AP7, Q8C7D2, Q96SW2
Gene Symbols
CRBN
Immunogen
A synthesized peptide derived from human CRBN(Accession Q96SW2), corresponding to amino acid residues D217-N267.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total CRBN
- CRBN, a member of the Lon protease protein family, plays a role in brain development
- It is a component of the DCX (DDB1-CUL4-X-box) E3 protein ligase complex, a complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins and is required for limb outgrowth and expression of the fibroblast growth factor FGF8
- CRBN is thought to regulate the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1
- It is widely expressed and highly expressed in brain.