MAST2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5106510-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA5106510 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
MAST2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAST2
Gene Alias
KIAA0807; Mast2; MAST205; microtubule associated serine/threonine kinase 2; microtubule associated testis specific serine/threonine protein kinase; microtubule-associated serine/threonine-protein kinase 2; Mtssk
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17776, 23139, 313819
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q60592, Q6P0Q8
Gene Symbols
MAST2
Immunogen
A synthesized peptide derived from human MAST2(Accession Q6P0Q8), corresponding to amino acid residues K1183-R1233.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total MAST2
- Syntrophin is an adapter protein that functions to bind certain signaling molecules to the dystrophin-associated protein complex
- This complex connects the extracellular matrix to the intracellular cytoskeleton for construction and maintenance of the postsynaptic structures in the neuromuscular junction and the central nervous system
- Microtubule-associated serine/threonine-protein kinase 2 (MAST205) is a testis-specific, cytoplasmic protein that functions in a multi-protein complex in the maturation of spermatids
- MAST205 is involved in linking the dystrophin/utrophin network with microtubule filaments via Syntrophin
- By forming a complex with TRAF6, MAST205 regulates lipopolysaccharide-induced IL-12 synthesis in macrophages
- This leads to the inhibition of TRAF6 NF-kappa-B activation
- Two isoforms exist for MAST205 due to alternative splicing
- Isoform 1 represents the full length protein, while isoform 2 lacks the residues 327-396 and 1091-1113
- The N-terminus of MAST205 must be phosphorylated in order for ubiquitination to occur at the same site
- This ubiquitination leads to the degradation of MAST205 via proteasome-mediated proteolysis.