PDEF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5107026-Each-of-1 | In Stock | ₹ 49,439.50 |
PIPA5107026 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,439.50
GST (18%): ₹ 8,899.11
Total Price: ₹ 58,338.61
Antigen
PDEF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Spdef
Gene Alias
bA375E1.3; PDEF; Prostate epithelium-specific Ets transcription factor; prostate specific ets transcription factor; prostate-derived Ets factor; Prostate-specific Ets; Pse; SAM pointed domain containing ets transcription factor; SAM pointed domain-containing Ets transcription factor; SPDEF
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
25803
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene Accession No.
O95238
Gene Symbols
Spdef
Immunogen
Synthetic peptide located within the following region: FKIEDSAQVA RLWGIRKNRP AMNYDKLSRS IRQYYKKGII RKPDISQRLV
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% PDEF (prostate-derived Ets factor) is a 37.5-kDa protein that acts as an androgen-independent transcriptional activator for the PSA (prostate specific antigen) promoter
- It also interacts directly with the DNA binding domain of androgen receptor and enhances androgen-mediated activation of the PSA promoter
- PDEF was shown to have transcript levels 192-fold higher in the peripheral blood of some breast cancer patients in comparison with normal individuals
- PDEF mRNA is also frequently over-expressed in human breast tumors as well as in human ovarian tumors
- In ovarian tumors, PDEF expression seems to down-modulate malignant potential, and thus provides a rationale to screen for drugs that induce PDEF expression in epithelial ovarian tumors.