RNF128 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5107244-Each-of-1 | In Stock | ₹ 46,858.50 |
PIPA5107244 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,858.50
GST (18%): ₹ 8,434.53
Total Price: ₹ 55,293.03
Antigen
RNF128
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RNF128
Gene Alias
1300002C13Rik; AI987883; E3 ubiquitin-protein ligase RNF128; Gene related to anergy in lymphocytes protein; goliath-related E3 ubiquitin-protein ligase 1; Grail; Greul1; MNCb-3816; RGD1566282; RING finger protein 128; ring finger protein 128, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase RNF128; RNF128; RP11-150F24.1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
66889, 79589
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1.0 mg/mL
Formulation
PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene Accession No.
Q8TEB7, Q9D304
Gene Symbols
RNF128
Immunogen
Synthetic peptide located within the following region: LEEHVQSTNE SLQLVNHEAN SVAVDVIPHV DNPTFEEDET PNQETAVREI
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Sequence homology: Cow: 86%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93% GRAIL is a type I transmembrane protein that localizes to the endocytic pathway and contains a PA (protease associated) domain and a RING-type zinc finger domain
- It is a ubiquitin-protein isopeptide ligase (E3) necessary for the induction of CD4(+) T cell anergy in vivo and induced expression of this protein was observed in anergic CD4 (+) T cells, which suggested a role in the induction of anergic phenotype
- It is differentially expressed in naturally occurring and peripherally induced CD25 (+) T regulatory cells and the expression is linked to the conversion of these cells to a regulatory phenotype
- Expression of GRAIL in retrovirally transduced T cell hybridomas limits activation-induced IL-2 and IL-4 cytokine production
- It also functions in the patterning of the dorsal ectoderm and sensitizes ectoderm to respond to neural-inducing signals.