PIPA5109530

CHM Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5109530-Each-of-1 In Stock ₹ 46,502.50

PIPA5109530 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

CHM

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CHM

Gene Alias

CHM; CHM, Rab escort protein 1; choroideraemia protein homolog; choroideremia (Rab escort protein 1); Choroideremia protein; Choroideremia protein homolog; choroidermia; choroidermia (RAB escort protein 1); DXS540; GGTA; HSD-32; Rab escort protein 1; rab proteins geranylgeranyltransferase component A 1; REP1; REP-1; TCD; TCD protein

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1121

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.07 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P24386

Gene Symbols

CHM

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 120-210 of human CHM (NP_000381.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: KNHALVTSAN STEAADSAFL PTEDESLSTM SCEMLTEQTP SSDPENALEV NGAEVTGEKE NHCDDKTCVP STSAEDMSEN VPIAEDTTEQ P Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex
  • Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction
  • The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane
  • Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.