CLN3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5109553-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5109553 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CLN3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CLN3
Gene Alias
AI323623; batten disease protein; Battenin; BTS; ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease); ceroid-lipofuscinosis, neuronal 3; CLN 3; Cln3; CLN3, battenin; Cln3p; JNCL; MGC102840; Protein CLN3
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1201, 12752, 293485
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
2.91 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.
Q13286, Q61124
Gene Symbols
CLN3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human CLN3 (NP_0010358971)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MGGCAGSRRR FSDSEGEETV PEPRLPLLDH QGAHWKNAVG FWLLGLCNNF SYVVMLSAAH DILSHKRTSG NQSHVDPGPT PIPHNSSSRF DCNSVSTAAV LLADILPTLV IKLLAPLGLH LLPYSPRVLV SGICAAGSFV LVAFSHSVGT SLCGVVFASI SSGLGEVTFL SLTAFYPRAV ISWWSSGTGG AGLLGALSYL GLTQAGLSPQ QTLLSMLGIP ALLLASYFLL LTSPEAQDPG GEEEAESAAR QPLIRTEAPE SKPGSSSSLS LRERWTVFKG CLN3 is a highly glycosylated, hydrophobic, 438-amino acid protein with 6 transmembrane domains
- The CLN3 protein localizes to the lysosomal membrane and plays a role in lysosomal function
- It may act as a chaperone involved in the folding and unfolding of other proteins, namely subunit C of the ATP synthase complex
- Mutations in the CLN3 gene cause Batten disease, a recessively inherited neurodegenerative disorder of childhood caused by lysosomal accumulation of hydrophobic material, mainly ATP synthase subunit C
- Batten disease is the most common form of a group of disorders known as neuronal ceroid lipofuscinoses (NCLs)
- Symptoms of Batten disease include progressive loss of vision, seizures, and psychomotor disturbances.