PIPA5109633

DHH Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5109633-Each-of-1 In Stock ₹ 46,502.50

PIPA5109633 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

DHH

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Dhh

Gene Alias

C78960; desert hedgehog; desert hedgehog protein; Desert hedgehog protein C-product; Desert hedgehog protein N-product; Dhh; GDXYM; HHG-3; SRXY7

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13363, 50846, 84380

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

3.7 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

O43323, Q61488

Gene Symbols

Dhh

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 199-396 of human DHH (NP_066382.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: CFPGNATVRL WSGERKGLRE LHRGDWVLAA DASGRVVPTP VLLFLDRDLQ RRASFVAVET EWPPRKLLLT PWHLVFAARG PAPAPGDFAP VFARRLRAGD SVLAPGGDAL RPARVARVAR EEAVGVFAPL TAHGTLLVND VLASCYAVLE SHQWAHRAFA PLRLLHALGA LLPGGAVQPT GMHWYSRLLY RLAEELLG This gene encodes a member of the Hedgehog family
  • The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis
  • This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signaling activity while the C-terminal portion is involved in precursor processing
  • More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism
  • Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy
  • This protein may be involved in both male gonadal differentiation and perineurial development.