INPP5E Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5109860-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5109860 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
INPP5E
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Inpp5e
Gene Alias
1200002L24Rik; 5-phosphatase that induces arborization; 72 kDa inositol polyphosphate 5-phosphatase; 72kDa; CORS1; CPD4; inositol polyphosphate 5-phosphatase; inositol polyphosphate-5-phosphatase E; inositol polyphosphate-5-phosphatase, 72 kDa; INPP5E; JBTS1; mKIAA0123; MORMS; Pharbin; phosphatidylinositol 4,5-bisphosphate 5-phosphatase; Phosphatidylinositol polyphosphate 5-phosphatase type IV; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase; phosphatidylinositol-4,5-bisphosphate 5-phosphatase; PPI5PIV
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
114089, 56623, 64436
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
2.94 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q9JII1, Q9NRR6, Q9WVR1
Gene Symbols
Inpp5e
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 510-630 of human INPP5E (NP_063945.2).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: LIREMRKGSI FKGFQEPDIH FLPSYKFDIG KDTYDSTSKQ RTPSYTDRVL YRSRHKGDIC PVSYSSCPGI KTSDHRPVYG LFRVKVRPGR DNIPLAAGKF DRELYLLGIK RRISKEIQRQ Q INPP5E (inositol polyphosphate 5-phosphatase), also known as phosphatidylinositol polyphosphate 5-phosphatase type IV, is a 644 amino acid peripheral membrane protein associated with Golgi stacks
- Belonging to the inositol-1, 4, 5-trisphosphate 5-phosphatase type IV family, INPP5E converts phosphatidylinositol-3, 4, 5-triphosphate (PtdIns 3, 4, 5-P3) to PtdIns-P2
- While inactive towards water soluble inositol phosphates, the activity of INPP5E is specific for lipid substrates
- INPP5E becomes phosphorylated upon DNA damage and is expressed in brain, heart, pancreas, testis and spleen
- Defects in INPP5E are the cause of Joubert syndrome type 1 (JBTS1), a disorder presenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay
- In addition, mutations in the INPP5E gene may lead to mental retardation-truncal obesity-retinal dystrophy-micropenis (MORMS), an autosomal recessive disorder characterized by moderate mental retardation, truncal obesity, congenital non-progressive retinal dystrophy, and micropenis in males.