MOV10 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5109971-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5109971 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
MOV10
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MOV10
Gene Alias
Armitage homolog; C77703; capping protein (actin filament) muscle Z-line, alpha 1; Capza1; fSAP113; functional spliceosome-associated protein 113; gb110; Helicase MOV-10; KIAA1631; Moloney leukemia virus 10; moloney leukemia virus 10 protein; Mov10; Mov-10; Mov10 RISC complex RNA helicase; Mov10, Moloney leukemia virus 10; Mov10, Moloney leukemia virus 10, homolog; putative helicase MOV-10
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17454, 310756, 4343
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.42 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P23249, Q9HCE1
Gene Symbols
MOV10
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human MOV10 (NP_066014.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MPSKFSCRQL REAGQCFESF LVVRGLDMET DRERLRTIYN RDFKISFGTP APGFSSMLYG MKIANLAYVT KTRVRFFRLD RWADVRFPEK RRMKLGSDIS KHHKSLLAKI FYDRAEYLHG KHGVDVEVQG PHEARDGQLL IRLDLNRKEV LTLRLRNGGT QSVTLTHLFP LCRTPQFAFY NEDQELPCPL GPGECYELHV HCKTSFVGYF PATVLWELLG PGESGSEGAG TFYIARFLAA VAHSPLAAQL KPMTPFKRTR ITGNPVVTNR IEEGERPDRA KGYDLELSMA LGTYYPPPRL RQLLPMLLQG 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs (PubMed:24726324)
- Required for microRNA (miRNA)-mediated gene silencing by the RNA-induced silencing complex (RISC)
- Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC (PubMed:16289642, PubMed:17507929, PubMed:22791714)
- In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2 (PubMed:25464849)
- Restricts retrotransposition of long interspersed element-1 (LINE-1) in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1 (PubMed:30122351, PubMed:23093941)
- Facilitates LINE-1 uridylation by TUT4 and TUT7 (PubMed:30122351)
- Required for embryonic viability and for normal central nervous system development and function
- Plays two critical roles in early brain development: suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol
- May function as a messenger ribonucleoprotein (mRNP) clearance factor (PubMed:24726324)
- Exhibits antiviral activity against dengue virus (DENV) (PubMed:27974568)
- [UniProt]