N6AMT2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5110010-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5110010 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
N6AMT2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Eef1akmt1
Gene Alias
2510005D08Rik; AW045965; Ayu21-96; DMNT2; DNMT2; EEF1A lysine methyltransferase 1; Eef1akmt1; ESP13; eukaryotic translation elongation factor 1 alpha lysine methyltransferase 1; Gt(Ayu21)96Imeg; Gt(pU21)96Imeg; GtAyu21-96; M.HsaIIP; N(6)-adenine-specific DNA methyltransferase 2; N-6 adenine-specific DNA methyltransferase 2 (putative); N6AMT2; Protein-lysine N-methyltransferase N6AMT2; PuMet; RGD1306762; RNMT1; RP11-406H21.1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
221143
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.67 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q8WVE0
Gene Symbols
Eef1akmt1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-214 of human N6AMT2 (NP_777588.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MSDLEDDETP QLSAHALAAL QEFYAEQKQQ IEPGEDDKYN IGIIEENWQL SQFWYSQETA LQLAQEAIAA VGEGGRIACV SAPSVYQKLR ELCRENFSIY IFEYDKRFAM YGEEFIFYDY NNPLDLPERI AAHSFDIVIA DPPYLSEECL RKTSETVKYL TRGKILLCTG AIMEEQAAEL LGVKMCTFVP RHTRNLANEF RCYVNYDSGL DCGI Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development
- Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer
- To date, 3 families of mammalian DNA methyltransferase genes have been identified which include Dnmt1, Dnmt2 and Dnmt3
- Dnmt1 is constitutively expressed in proliferating cells and inactivation of this gene causes global demethylation of genomic DNA and embryonic lethality
- Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation
- Dnmt2 contains all the sequence motifs diagnostic of DNA (cytosine-5)-methyltransferases but appears to lack the large N-terminal regulatory domain common to other eukaryotic methyltransferases.