PIPA5110085

PDCD6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5110085-Each-of-1 In Stock ₹ 46,502.50

PIPA5110085 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

PDCD6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Pdcd6

Gene Alias

Alg2; alg-2; ALG-257; Apoptosis-linked gene 2 protein; Apoptosis-linked gene 2 protein homolog; AV299538; MA-3; PDCD6; PEF1B; PMP41; probable calcium-binding protein ALG-2; programmed cell death 6; programmed cell death protein 6; PS2

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10016, 18570, 308061

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

0.90 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

G3V7W1, O75340, P12815

Gene Symbols

Pdcd6

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human PDCD6 (NP_037364.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MAAYSYRPGP GAGPGPAAGA ALPDQSFLWN VFQRVDKDRS GVISDTELQQ ALSNGTWTPF NPVTVRSIIS MFDRENKAGV NFSEFTGVWK YITDWQNVFR TYDRDNSGMI DKNELKQALS GFGYRLSDQF HDILIRKFDR QGRGQIAFDD FIQGCIVLQR LTDIFRRYDT DQDGWIQVSY EQYLSMVFSI V An increased intracellular Ca2+ concentration induces apoptotic cell death
  • Transiently elevated Ca2+ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis
  • ALG-2 (for apoptosis-linked gene 2) is a Ca2+ -binding protein that participates in regulatory events occuring late in the apoptotic program and where several death signals converge
  • ALG-2 is a protein expressed in normal brain, and to a greater extent in ischemic brain
  • The ALG-2 protein contains five EF-hand-like motifs and shares homology with members of the penta EF-hand family, which includes Calpain small subunits sorcin and Grancalcin.