PIPA5110249

PZP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5110249-Each-of-1 In Stock ₹ 46,502.50

PIPA5110249 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

PZP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PZP

Gene Alias

A1m; A1m {ECO:0000312; A2m; AI893533; alpha 1 macroglobulin; alpha-1-M; Alpha-1-macroglobulin; alpha-1-macroglobulin 165 kDa subunit; Alpha-1-macroglobulin 45 kDa subunit; alpha-2-M; alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6; CPAMD6; EMBL:AAA40723.1}; MAM; Pregnancy zone protein; pregnancy-zone protein; Pzp; PZP, alpha-2-macroglobulin like

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11287, 252922, 5858

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.92 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

P20742, Q61838, Q63041

Gene Symbols

PZP

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 620-740 of human PZP (NP_002855.2).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: VKDLTNFPDN VDQQEEEQGH CPRPFFIHNG AIYVPLSSNE ADIYSFLKGM GLKVFTNSKI RKPKSCSVIP SVSAGAVGQG YYGAGLGVVE RPYVPQLGTY NVIPLNNEQS SGPVPETVRS Y The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin
  • The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases
  • This protein contains cleavage sites for several proteinases
  • Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity
  • This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients.