SEPT5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5110351-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5110351 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
SEPT5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SEPTIN5
Gene Alias
5-Sep; CDCREL; CDCREL1; CDCREL-1; CDCrel-1A; cell division control related protein 1; cell division control-related protein 1; H5; HCDCREL-1; peanut-like 1; peanut-like 1 homolog; peanut-like protein 1; platelet glycoprotein Ib beta chain; Pnutl1; Sept5; septin 5; SEPTIN5; septin-5
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116728, 18951, 5413
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.11 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q99719, Q9JJM9, Q9Z2Q6
Gene Symbols
SEPTIN5
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human Septin 5 (NP_0026792)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MSTGLRYKSK LATPEDKQDI DKQYVGFATL PNQVHRKSVK KGFDFTLMVA GESGLGKSTL VHSLFLTDLY KDRKLLSAEE RISQTVEILK HTVDIEEKGV KLKLTIVDTP GFGDAVNNTE CWKPITDYVD QQFEQYFRDE SGLNRKNIQD NRVHCCLYFI SPFGHGLRPV DVGFMKALHE KVNIVPLIAK ADCLVPSEIR KLKERIREEI DKFGIHVYQF PECDSDEDED FKQQDRELKE SAPFAVIGSN TVVEAKGQRV RGRLYPWGIV EVENQAHCDF VKLRNMLIRT HMHDLKDVTC DVHYENYRAH CIQQMTSKLT QDSRMESPIP ILPLPTPDAE TEKLIRMKDE ELRRMQEMLQ RMKQQMQDQ This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins
- Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization
- Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells
- This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes
- A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia
- Two transcripts of this gene, a major one of 2.2 kb and a minor one of 3.5 kb, have been observed
- The 2.2 kb form results from the utilization of a non-consensus polyA signal (AACAAT)
- In the absence of polyadenylation from this imperfect site, the consensus polyA signal of the downstream neighboring gene (GP1BB; platelet glycoprotein Ib) is used, resulting in the 3.5 kb transcript
- An alternatively spliced transcript variant with a different 5' end has also been identified, but its full-length nature has not been completely determined.