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PIPA5110773

SLITRK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5110773-Each-of-1 In Stock ₹ 48,905.50

PIPA5110773 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

SLITRK1

Classification

Polyclonal

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q96PX8

Gene Symbols

SLITRK1

Immunogen

Recombinant Protein corresonding to Human SLITRK1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry

Conjugate

Unconjugated

Gene

SLITRK1

Gene Alias

3200001I04Rik; KIAA1910; Leucine-rich repeat-containing protein 12; LRRC12; RP11-395N17.1; SLIT and NTRK like family member 1; SLIT and NTRK-like family, member 1; SLIT and NTRK-like protein 1; slit and trk like gene 1; SLITRK1; Sltk1; TTM; UNQ233/PRO266

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

114798

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Immunogen sequence: GNRLKTLPYE EVLEQIPGIA EILLEDNPWD CTCDLLSLKE WLENIPKNAL IGRVVCEAPT RLQGKDLNET TEQDLCPLKN RVDSSLPAPP AQEETFAPGP LPTPFKTNGQ EDHATPGSAP NGGTKIPGNW QIKIRPTAAI ATGSSRNKP SLIT and NTRK-like family 1 (Slitrk1) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein
  • These proteins are also homologous to trk neurotrophin receptors in their intracellular domains
  • Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family
  • For example, Slitrk1 is expressed primarily in mature neurons
  • Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth
  • While Slitrk1 variants have been suggested associated with Tourette's Syndrome, it is thought to play only a minor role if at all.