RIT1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5111371-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA5111371 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
RIT1
Classification
Polyclonal
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q92963
Gene Symbols
RIT1
Immunogen
Recombinant Protein corresonding to Human RIT1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
RIT1
Gene Alias
GTP-binding protein Rit1; GTP-binding protein Roc1; MGC125864; MGC125865; NS8; Ras like without CAAX 1; ras-like protein expressed in many tissues; Ras-like without CAAX 1; ras-like without CAAX protein 1; RGD1559874; RIBB; Ric-like, expressed in many tissues; RIT; RIT1; ROC1; si:ch211-93a2.3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6016
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Immunogen sequence: AYRYYIDDVF HALVREIRRK EKEAVLAMEK KSKPKNSVWK RLKSPFRKKK DSVT Rit and its neuron-specific homologue, Rin, define a recently discovered subfamily of Ras-related GTPases
- Rit and Rin are membrane-associated in spite of the fact that they lack a CAAX box or similar C-terminal lipidation motif
- Rit and Rin display 64% amino acid sequence identity and share a unique nine amino acid effector domain (DPTIEDAYK) that is 100% conserved between the murine and human proteins
- Although the effector domain sequences of Rit and Rin are very similar to that of Ras, Rit and Rin have been shown to interact with the known Ras-binding proteins RalGDS, Rlf and AF-6, but not the Raf kinases, RIN1 or the p110 subunit of PI3 kinase
- For this reason, it has been suggested that Rit and Rin may play important roles in the regulation of signaling pathways distinct from those controlled by Ras.