PIPA5111534
HES6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5111534-Each-of-1 | In Stock | ₹ 52,599.00 |
PIPA5111534 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,599.00
GST (18%): ₹ 9,467.82
Total Price: ₹ 62,066.82
Antigen
HES6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HES6
Gene Alias
AI326893; bHLHb41; bHLHc23; C-HAIRY1; class B basic helix-loop-helix protein 41; Hairy and enhancer of split 6; hes family bHLH transcription factor 6; hes6; HES-6; Transcription cofactor HES-6
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55502
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q96HZ4
Gene Symbols
HES6
Immunogen
Recombinant Protein corresonding to Human HES6
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: PIPSPPGPGD DLCSDLEEAP EAELSQAPAE GPDLVPAALG SLTTAQIARS VWRPW The HES family members form a complex with TLE, the mammalian homologue of Groucho, and this interaction is mediated by the carboxy terminal WRPW motif of the HES proteins
- The HES/TLE complex functions by directly binding to DNA, instead of interfering with activator proteins
- Most HES family members, including HES1 and HES5, preferentially bind to the N box (CACNAG) as opposed to the E box (CANNTG)
- HES2 binds to both N and E box sites, while HES6 does not bind DNA
- Rather, HES6 inhibits HES1 activity, thereby promoting transcription
- HES1 and HES2 are expressed in a variety of adult and embryonic tissues
- HES3 is expressed exclusively in cerebellar Purkinje cells, and HES5 is found solely in the nervous system
- HES6 is produced in brain as well as in the limb buds of developing embryos.