ACVR1B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5111573-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA5111573 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
ACVR1B
Classification
Polyclonal
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P36896
Gene Symbols
ACVR1B
Immunogen
Recombinant Protein corresonding to Human ACVR1B
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Gene
ACVR1B
Gene Alias
6820432J04; activin A receptor type 1B; activin A receptor type IB; activin A receptor, type 1B; activin A receptor, type IB; activin A receptor, type II-like kinase 4; activin receptor type IB; Activin receptor type-1B; activin receptor-like kinase 4; ACTRI; ActRIB; ActR-IB; ACVR1A; Acvr1b; ACVRLK2; ACVRLK4; ALK2; Alk4; ALK-4; FOP; Serine/threonine-protein kinase receptor R2; SKR1; SKR2; TSRI
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
91
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Immunogen sequence: GVQALLCACT SCLQANYTCE TDGACMVSIF NLDGMEHHVR TCIPKVEL ACVR1B is a serine/threonine kinase involved in signal transduction and cellular communication
- Several truncated ACVR1B isoforms have been reported to be exclusively expressed in human pituitary tumors
- Mutations of ACVR1B have been observed in pancreatic adenocarcinomas
- Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors
- ACVR1B encodes activin A type IB receptor, composed of 11 exons
- Alternative splicing and alternative polyadenylation result in 3 fully described transcript variants
- The mRNA expression of variants 1, 2, and 3 is confirmed, and a potential fourth variant contains an alternative exon 8 and lacks exons 9 through 11, but its mRNA expression has not been confirmed.