MMP19 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5111664-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA5111664 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
MMP19
Classification
Polyclonal
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q99542
Gene Symbols
MMP19
Immunogen
Recombinant Protein corresonding to Human MMP19
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Conjugate
Unconjugated
Gene
MMP19
Gene Alias
CODA; matrix metallo protease; matrix metallopeptidase 19; matrix metalloproteinase 19; matrix metalloproteinase RASI; Matrix metalloproteinase-18; matrix metalloproteinase-19; matrix metalloproteinase-beta19; MMP; MMP18; MMP-18; Mmp19; MMP-19; MMPs; Rasi; RASI-1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4327
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Immunogen sequence: PVDYLSQYGY LQKPLEGSNN FKPEDITEAL RAFQEASELP VSGQLDDATR ARMRQPRCGL EDPFNQKTLK YLLLGRWRKK HLTFRILNL MMP-19 (RASI-1, MMP-18) is a 508 amino acid peptide, originally isolated as an autoantigen from the synovium of a patient suffering from rheumatoid arthritis (RA)
- Its presence on the surface of activated PBMCs, TH1 lymphocytes, and Jurkat T lymphoma cells in the synovium of acute RA patients, suggests that MMP-19 plays a role in RA-associated joint tissue destruction
- MMP-19 exists in the smooth muscle cells of the tunica media of large blood vessels of the RA patient, but not in the endothelial cell layer
- Acutely inflamed tissue synovial capillaries strongly express MMP-19 in the cytoplasm
- Regulated induction of MMP-19 in capillary endothelial cells during acute inflammation suggest a role in angiogenesis
- MMP-19 is a single 2.7kb transcript found in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis, colon, and heart.