PIPA5111704
ITPKB Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5111704-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA5111704 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
ITPKB
Classification
Polyclonal
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P27987
Gene Symbols
ITPKB
Immunogen
Recombinant Protein corresonding to Human ITPKB
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry
Conjugate
Unconjugated
Gene
ITPKB
Gene Alias
1110033J02Rik; E130307H12Rik; Inositol 1,4,5-trisphosphate 3-kinase B; inositol-trisphosphate 3-kinase B; insP 3-kinase B; IP3 3-kinase B; IP3-3KB; IP3K; IP3K B; IP3KB; IP3K-B; Itpkb; PIG37; proliferation-inducing protein 37
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3707
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Immunogen sequence: GGSPTLGLLG GSPSAQPGTG NVEAGIPSGR MLEPLPCWDA AKDLKEPQCP PGDRVGVQPG NSRVWQGTME KAGLAWTRGT GVQSEGTWES QR Inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) regulates the level of calcium within the cell by releasing calcium from intracellular stores
- Ins(1,4,5)P3 is phosphorylated by inositol 1,4,5-trisphosphate 3-kinase (IP3K) to form inositol 1,3,4,5-tetrakisphosphate (Ins(1,4,5)P4), which is is thought to regulate the influx of calcium across the plasma membrane
- IP3K exists as three isoforms, IP3KA, B, and C
- IP3KA, the most highly characterized isoform, is expressed in rat brain and testis
- IP3KB is expressed in various rat tissues such as lung, thymus, testis, brain, and heart
- IP3K activity is stimulated in the presence of calmodulin via phosphorylation by cAMP-dependent protein kinase, protein kinase C, or calcium/calmodulin dependent protein kinase II and, subsequently, mediates the inositol phosphate signaling pathways.