PIPA5111710

TEK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5111710-Each-of-1 In Stock ₹ 47,615.00

PIPA5111710 - Each of 1

₹ 47,615.00

In Stock

Quantity

1

Base Price: ₹ 47,615.00

GST (18%): ₹ 8,570.70

Total Price: ₹ 56,185.70

Antigen

TEK

Classification

Polyclonal

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q02763

Gene Symbols

TEK

Immunogen

Recombinant Protein corresonding to Human TEK

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunofluorescence

Conjugate

Unconjugated

Gene

TEK

Gene Alias

AA517024; Angiopoietin-1 receptor; CD202b; CD202b antigen; EC 2.7.10; EC 2.7.10.1; Endothelial tyrosine kinase; hTIE2; Hyk; mTIE2; p140 TEK; STK1; Tek; TEKT1; Tektin-1; Tie2; Tie-2; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor Tie-2; VMCM; VMCM1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7010

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Immunogen sequence: VISWTILDGY SISSITIRYK VQGKNEDQHV DVKIKNATIT QYQLKGLEPE TAYQVDIFAE NNIGSSNPAF SHELVTLPES QAPADL TIE2, also known as TEK tyrosine kinase, TIE2 gene is mapped to 9p21.2
  • This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family
  • The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats
  • The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development
  • Immunoblotting showed that TIE2 expression was increased by thyroid-stimulating hormone and agents that increased intracellular cAMP
  • HSCs expressing the receptor tyrosine kinase TIE2 are quiescent and antiapoptotic and comprise a side population of HSCs that adhere to osteoblasts in the bone marrow niche.